Professor Brenda Costa’s group in Italy has published new important data, proving that PEA is more than just a natural painkiller. PEA also has intrinsic positive effects on diabetes, because it is protecting the cells of the pancreas against harm.

Costa’s group explored the ability of PEA to reduce chronic pain in diabetes. Their findings supported that PEA relieves chronic pain, counteracts nerve growth factor deficits, improves insulin level, preserves the Langerhans cells and reducing the development of complications in diabetic mice. These results suggest that PEA could be extremely useful in diabetic patients. Not only as pain reliever! PEA clearly does much more to protect our cells.

The preparations with the PEA-opt® quality mark contain absolutely NO chemical or pharmaceutical excipients (such as magnesium stearate, povidone, sorbitol) or coloring agents (such as titanium dioxide). After all, modern and conscientious consumers do not want any mixes that contain redundant chemical substances or coloring agents, certainly if there are indications that these substances are harmful to our health.

For pain relief and for inhibiting inflammation, most patients choose:

  • PEA capsules produced in the Netherlands by Russell
  • PEA tablets produced in Italy by Epitech

Literature PEA-diabetes

Keppel Hesselink JM, Costagliola C, Fakhry J, Kopsky DJ. Palmitoylethanolamide, a Natural Retinoprotectant: Its Putative Relevance for the Treatment of Glaucoma and Diabetic Retinopathy. J Ophthalmol. 2015; 2015:430596. doi: 10.1155/2015/430596.

Hesselink JM, Hekker TA. Therapeutic utility of palmitoylethanolamide in the treatment of neuropathic pain associated with various pathological conditions: a case series.

J Pain Res. 2012; 5:437-42. doi: 10.2147/JPR.S32143.

Donvito G, Bettoni I, Comelli F, Colombo A, Costa B. Palmitoylethanolamide relieves pain and preserves pancreatic islet cells in a murine model of diabetes.

CNS Neurol Disord Drug Targets. 2015;14(4):452-62.