Vaginal pain is also known as vulvodynia, especially as the cause remains unclear. Vaginal pains are quite stressful and uncomfortable. Vaginal pain also negatively influences the patient’s quality of life.

In most cases, vaginal pain and burning are caused by a yeast infection called Candida. Candida is a small one cellular plant, with a potential to grow in our body, for instance in the throat in cases of cancer. But it can also grow elsewhere if the natural defense of our body is not optimal. The body tries to get rid of the Candida cells via inflammation with redness and itching.

However, quite regularly no Candida is found in the case of burning vaginal pains and also no bacteria that explain the symptoms. Then there is a problem, what to do? The vagina can look perfectly normal but still, there is pain and/or itch.

With the availability of the natural pain relieving substance palmitoylethanolamide, which also has an anti-inflammatory effect, treatment of burning sensation and redness of the vagina became possible. This supplement is available as PEA capsules and as PEA cream.

The Italian PEA tablets are also available in Italy. However, PEA capsules contain solely pure palmitoylethanolamide and no chemical or pharmaceutical additives and fillers.

For pain relief and for inhibiting inflammation, most patients choose:

  • PEA capsules produced in the Netherlands by Russell
  • PEA tablets produced in Italy by Epitech

Dose recommendation in case of vaginal pains

Always use a dose of 1200mg per day, 400 mg capsules 3 times daily. PEA cream can also be applied several times a day.

Vaginal pain: not right at all

Due to all kinds of factors, our body doesn’t easily succeed to kill the yeast infection. The majority of women will have an infection due to this yeast at some point in their lives. In such a case, you notice something isn’t quite right in the vaginal region when you start to feel itching, painful or burning sensations in or around the vagina. Also, the, normally clear, vaginal discharge might change color, scent, and consistency.

This vaginal yeast infection is caused by the yeast named Candida albicans. However, remember that there are other causes besides this yeast infection!

Candida, the cause of a vaginal yeast infection

How do you recognize a vaginal yeast infection? A number of signs and symptoms are important here.

Symptoms of vaginal Candida infections

First of all the labia may look different, they become red and a little swollen. The sensation will also feel different, accompanied by the redness and swelling, you will notice itching and a burning pain on both the inside of the vagina as well as around the labia. This causes intercourse to be less enjoyable or even unpleasant.

The burning, itch, and pain, even burning pain can also be quite unpleasant during urination.

In summary:

  1. Red, swollen labia and itching
  2. Burning sensation and pain in the vagina
  3. Pain during intercourse
  4. Pain during urination
  5. Increase of and change of vaginal discharge

These types of complaints and symptoms can be caused by a vaginal yeast infection. If this is the case, go and see a doctor, who will probably perform an internal examination. Or, based on your complaints, immediately prescribe an antifungal cream.A clear red coloration of the vaginal wall accompanied by a slightly abnormal discharge, for example, more grainy or discolored, all indicate an inflammation due to yeast.

To be completely sure that the symptoms are caused by a yeast infection, a small quantity of discharge has to be taken from the vagina, which can be examined under a microscope. The yeast cells are easy to recognize under a microscope.

Vaginal pains caused by Candida yeast

Experts say Candida albicans is a yeast that is ‘ubiquitous’, which means this yeast is present everywhere in the body including the skin, mouth, intestines and also the vagina. It’s kind of like a pet, or more like a houseplant. But this plant can take over your entire room and turn it into a jungle.

If that happens you will get a yeast infection. The cause of infections is helped by a weakened immune system, which may be caused by diabetes, antibiotics or when the skin’s natural balance is disturbed by washing it with soap! Don’t do it! You don’t brush your teeth with soap either. Put it away, no soap in the vagina. Frequent sexual intercourse can also damage the vaginal mucosa and initiate an infection. And lastly, hormonal preparations, like the pill, can disturb the vaginal balance.

No Candida infection, but still vaginal pain, now what?

Pain in the vagina and no infection. If there is no infection, but still pain in the vagina, what do you do? Doctors refer to this as vulvodynia, but that doesn’t give much away. The word only indicates there is pain in the vagina. You’d think that the cause should be easy to find, but that’s not the case.

Vulvodynia causes women to have long-term pain and burning complaints. Strangely enough, these unexplained complaints are quite common. And because we are quite prudish, we wouldn’t be surprised if it’s even more common than what we currently think.

It’s estimated that 1 out of 25 to 50 women suffer from these chronic misunderstood pain complaints. Characteristic for these complaints is that there are no infections, no neurological abnormalities and on top of that no anatomical abnormalities. That’s great, you’re probably thinking, but what is it?

Vulvodynia: inflammation in the vagina like a war without an enemy

Vulvodynia: pain in the vagina but no infection by bacteria or Candida. We suspect the inflammation is like a war without an enemy. In other words, inflammation without infection. Bacteria, yeast or a virus are responsible for infections and cause an inflammatory response. If there is inflammation without infection we’re dealing with a war without enemy.

How can this be explained? It is thought that damage on the vaginal wall, for example by frequent sexual intercourse, can create a mild infection in the vagina. The continuous irritation of this mild chronic inflammation alarms the nervous system. This has been scientifically proven. Women with a localized provoked vulvodynia, as this is called, have an alarmed, hyperactive nervous system. The slightest stimuli alarm the body. [1]

PEA cream, a local cream together with PEA capsules in vulvodynia

Research showed some positive results from strong painkillers like anti-depressants, however, these often come with a range of negative side effects. At times, it’s also suggested to use a lidocaine gel, which causes the skin tissue to go numb and that’s not very pleasant for the vagina. That’s why a number of pain relieving creams have been developed that are gentle on the vagina and effectively decrease pain and itching. These creams contain special substances that calm the tissue of the vagina and include the bodily fatty acid palmitoylethanolamide (PEA) and a pain-relieving substance. There’s also a pure PEA cream, which only contains PEA.

To treat the unexplained pain when gynecologists cannot find the cause, we have PEA to our disposal, a natural pain relieving and anti-inflammatory substance. It is available as a supplement in capsules and. the correct dose is 400mg three times a day.


[1] Bohm-Starke N. | Medical and physical predictors of localized provoked vulvodynia. Acta Obstet Gynecol Scand. | 2010 Dec;89(12):1504-10. doi: 10.3109/00016349.2010.528368.