Friday, May 26, 2017

Palmitoylethanolamide influences local mast cell proliferation in canine atopic dermatitis.

Background: Despite the precise pathogenesis of atopic dermatitis (AD) is unknown, an immune dysregulation that causes Th2-predominant inflammation and an intrinsic defect in skin barrier...

Palmitoylethanolamide in neck pain

Purpose: Chronic neck/shoulder pain (CNSP) is one of the most common pain conditions. The understanding of mechanisms, including the peripheral balance between nociceptive and antinociceptive...

Palmitoylethanolamide for chronic lung fibrosis

Pulmonary fibrosis is a chronic condition characterized by progressive scarring of lung parenchyma. The aim of this study was to examine the effects of...

Palmitoylethanolamide can help in kidney failure

Hypertension is an important risk factor for kidney failure and renal events in the general population. Palmitoylethanolamide (PEA) is a member of the fatty...

Palmitoylethanolamide against chronic inflammation: its protective properties

Palmitoylethanolamide (PEA) is a peroxisome proliferator-activated receptor alpha (PPAR-α) ligand that exerts anti-inflammatory, analgesic and neuroprotective actions. PEA is synthetized from phospholipids through the...

Palmitoylethanolamide helps in fibromyalgia

Introduction: Fibromyalgia syndrome (FM) is characterized by persistent pain which is often refractory to common analgesic therapies and is particularly disabling. The objective of this...

Palmitoylethanolamide against inflammation in the gut: relevance in the treatment of...

Background and purpose: Palmitoylethanolamide (PEA), a naturally occurring acylethanolamide chemically related to the endocannabinoid anandamide, interacts with targets that have been identified in peripheral nerves...

Palmitoylethanolamide in colitis: new findings

Background and purpose: Palmitoylethanolamide (PEA) acts via several targets, including cannabinoid CB1 and CB2 receptors, transient receptor potential vanilloid type-1 (TRPV1) ion channels, peroxisome proliferatoractivated...

IBD and IBS: palmitoylethanolamide, a natural treatment focussing on gut homeostasis...

Inflammatory bowel diseases (IBD) and irritable bowel syndrome (IBS), are chronic inflammatory disorders, leading to abdominal pain, diarrhea and motility disturbances. In the gut endogenous...

Palmitoylethanolamide (PEA) decreases itch and eczema

Atopic dermatitis is a skin inflammation occurring in humans as well as in dogs. Atopic dermatitis (AD), is also referred to as atopic eczema....